Appendicitis
MONDO:0005649Acute inflammation of the vermiform appendix.
Also known as: inflammation of vermiform appendix, vermiform appendix inflammation, acute appendicitis, acute appendicitis with generalised peritonitis, acute appendicitis with generalized peritonitis, acute appendicitis with peritoneal abscess
78 clinical trials for this condition and its sub-types, 76 tagged with Appendicitis itself.
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Could an extra dose of antibiotics during appendix surgery cut infection risk?
Disease control OngoingThis study looks at whether giving an extra dose of the antibiotic cefoxitin during appendix removal surgery can better prevent infections compared to the usual single dose before surgery. Researchers will measure antibiotic levels in blood, fat, and appendix tissue from 46 parti…
Phase 1 • Sponsor: University of Michigan • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Probiotics may speed healing after burst appendix surgery
Disease control OngoingThis study tests whether giving a probiotic called Lactobacillus plantarum after surgery for a burst appendix can reduce inflammation, pain, and hospital stay. Researchers will measure white blood cell counts and pain levels in 50 adults. The goal is to see if probiotics help con…
Sponsor: Universitas Padjadjaran • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Can a simple antibiotic wash stop infections after appendix surgery in kids?
Disease control OngoingThis study looks at whether using an antibiotic solution to wash the surgical area during laparoscopic appendix removal can lower the chance of wound infections in children with a burst appendix. About 200 children aged 18 or younger will take part. The goal is to find a better w…
Phase 2 • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Which pain block works best for kids after appendix removal?
Symptom relief By invitation onlyThis study looks at 70 children aged 7 to 12 having appendix surgery. It compares two ultrasound-guided pain blocks to see which one reduces the need for extra pain medicine and improves recovery. The goal is to find a safer, more effective way to manage pain after surgery.
Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Study aims to predict who can skip surgery for appendicitis
Knowledge-focused OngoingThis study looks at 400 adults with acute appendicitis to figure out who can be treated with antibiotics alone and who needs surgery. Researchers will track lab results, imaging, and symptoms to see which approach works best for each patient. The goal is to help doctors choose th…
Sponsor: Sebahattin Celik MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC