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Can a simple antibiotic wash stop infections after appendix surgery in kids?

NCT ID NCT04039750

Disease control Sponsor: Prisma Health-Upstate Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using an antibiotic solution to wash the surgical area during laparoscopic appendix removal can lower the chance of wound infections in children with a burst appendix. About 200 children aged 18 or younger will take part. The goal is to find a better way to prevent infections after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2019

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

0 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male or female, age 18 years or younger 2. Scheduled to undergo laparoscopic appendectomy 3. Preoperative or intra-operative diagnosis of perforated appendicitis (PA). 4. Willingness to undergo treatments, provide written informed consent, and participate in follow-up. Exclusion Criteria: 1. Male or female older than 18 years of age 2. Declined to undergo laparoscopic appendectomy 3. Not willing to provide written informed consent or undergo randomization of treatment 4. Pregnancy

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Conditions

The condition(s) this trial relates to.

appendicitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perforated appendicitis

Contacts and locations

Locations

  • Prisma Health - Upstate

    Greenville, South Carolina, 29615, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.