Alcohol-related disorders

This study tests whether a telemedicine program that combines brief counseling with cognitive-behavioral therapy can help people with HIV reduce unhealthy alcohol use and improve their overall health. About 308 participants in Alabama will receive either the combined program or b…

This study tests a program called Khanya, where trained peers (people with lived substance use experience) help HIV patients stick to their medication and reduce drug or alcohol use. The program is offered in steps: a basic version first, then a more intensive one if needed. Rese…

This study tests whether online mindfulness-based relapse prevention (MBRP) helps people with alcohol use disorder maintain long-term recovery. About 470 adults who recently sought treatment or tried to cut back on drinking will either join MBRP video groups or be referred to onl…

This study tests whether an app-based early intervention can help reduce alcohol use and posttraumatic stress symptoms in people who have recently experienced sexual assault. Participants are randomly assigned to receive different versions of the THRIVE app, which includes activi…

This study tests whether a self-help handbook called the 5-Step Method can help family members cope with the stress of a relative's drug or alcohol misuse. 24 adults in the US will be split into two groups: one gets the handbook, the other does not. The goal is to see if the prog…

This pilot study tested whether a 'care navigator' could help people with substance use disorders follow through on treatment plans. The navigator worked alongside usual care coordinators to address barriers like language, income, or location. The study involved 74 patients and f…

This study tests whether a "Care Navigator" — a personal guide — can help people with substance use problems start and stay in treatment. About 360 adults who call a mental health access center will be randomly assigned to get usual care or extra help from a navigator. The goal i…

This study follows 300 patients with severe alcoholic hepatitis who receive early liver transplants, before the usual 6-month sobriety period. Researchers will track how many survive one year after transplant and how many return to drinking. The goal is to better understand the r…