Alcohol-related disorders

This study tested whether brief or in-depth counseling could help people living with HIV in Zambia reduce unhealthy alcohol use and improve HIV treatment. 680 adults who were on HIV medication and had hazardous drinking plus mental health or substance use issues took part. Partic…

This study tested a blended collaborative care model that uses telemedicine to integrate mental health treatment into primary care at smaller VA clinics serving rural veterans. Researchers enrolled 318 veterans who screened positive for depression, alcohol use disorder, or PTSD. …

This study tested whether semaglutide, a drug used for diabetes and weight loss, can safely reduce alcohol drinking in people with alcohol use disorder. 80 adults took either semaglutide or a placebo, and researchers tracked how much they drank over several weeks. The goal was to…

This study tested a school-based program called Preventure in 3,900 Canadian teens. The program targets four personality traits linked to substance misuse, aiming to delay or prevent alcohol and drug use. Researchers also measured whether delaying substance use helps protect cogn…

Researchers are testing whether a five-module internet-based treatment program with therapist support works as well as the same treatment given face-to-face in specialized addiction care. The trial enrolls adults in Stockholm County who drink harmfully or show signs of alcohol de…

This early-stage study tests whether diclofenac, an FDA-approved painkiller, can reduce alcohol cravings in people with alcohol use disorder. Researchers believe diclofenac may work by shifting brain chemistry away from harmful effects of alcohol. The study involves 24 adults who…

This study tested whether tailored online writing exercises could help sexual minority women, transgender, and nonbinary people who have experienced trauma. The goal was to reduce PTSD symptoms and heavy drinking. 131 participants completed the writing program and were followed f…

This study looked at 23 adults going through alcohol detox to see how the bacteria in their mouth and gut change over time. Researchers collected stool and mouth samples along with diet and mood questionnaires. The goal was to better understand the link between gut bacteria, anxi…

This study looked at whether using a Fitbit activity tracker can help people receiving inpatient treatment for alcohol use disorder increase their physical activity and improve their emotional state. Ninety adults in treatment wore the tracker and completed questionnaires about t…

This study looked at how the brains of people with alcohol use disorder respond to pictures of social situations and alcohol. Researchers used MRI scans to measure brain activity and tested whether a technique called neurofeedback could help people control their cravings. The stu…

This study looked at the best ways to bring FDA-approved digital treatments (reSET and reSET-O) for opioid and other substance use disorders into primary care clinics. Over 18,000 adults who screened positive for substance use took part. Researchers tested whether health coaching…