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Acute urate nephropathy
MONDO:0003652Urolithiasis in which the composition of the stones is predominantly urate.
Also known as: uric acid nephrolithiasis, uric acid urolithiasis
6 clinical trials for this condition and its sub-types, 4 tagged with Acute urate nephropathy itself.
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Can a diabetes drug and diet stop kidney stones?
Disease control CompletedThis study tested whether the diabetes drug pioglitazone, weight loss, or both can help prevent uric acid kidney stones in overweight people. Twenty-nine participants were randomly assigned to one of three groups for 24 weeks. The main goal was to see if these interventions could…
Phase 4 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Could a Weight-Loss pill also crush kidney stones?
Disease control CompletedThis pilot study tested whether a combination of phentermine and topiramate, two drugs used for weight loss, could help shrink uric acid kidney stones in obese people with type 2 diabetes or pre-diabetes. Nineteen participants were randomly assigned to receive the drug combo or c…
Phase 2 • Sponsor: University of Florida • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a common blood pressure drug lower uric acid in kids with kidney problems?
Disease control CompletedThis study looked at whether losartan, a blood pressure medicine, can lower uric acid levels in children with proteinuric nephropathies (kidney disease with protein in urine). Forty children already taking enalapril were randomly assigned to receive either losartan or continue en…
Phase 4 • Sponsor: Hospital General de Niños Pedro de Elizalde • Aim: Disease control
Last updated Jun 26, 2026 17:10 UTC
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New citrate cocktail may dissolve tough kidney stones without surgery
Disease control CompletedThis study tested a citrate mixture (citric acid, potassium bicarbonate, and sodium citrate) to dissolve coral-like urate kidney stones in 49 patients. The goal was to see if the treatment could shrink or eliminate stones, potentially avoiding surgery. Patients took a personalize…
Sponsor: Moscow State University of Medicine and Dentistry • Aim: Disease control
Last updated Jun 26, 2026 14:44 UTC