Acanthamoeba keratitis
MONDO:0005629Keratitis due to infection by acanthamoeba; it is usually associated with soft contact lens wear, particularly overnight wear.
Also known as: Acanthamoeba caused keratitis, keratitis, Acanthamoeba
13 clinical trials for this condition and its sub-types, 5 tagged with Acanthamoeba keratitis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Green light and pink dye take on tough eye infections
Disease control CompletedThis study tested whether adding a light-activated dye (rose bengal) to standard antibiotic or antifungal eye drops could improve vision in people with severe corneal infections. About 330 adults in India and Brazil with fungal or amoeba infections received either standard drops …
Phase 3 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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23 patients treated: new hope for rare eye infection?
Disease control CompletedThis study looked back at medical records of 23 people in Spain who had a rare eye infection called acanthamoeba keratitis. All patients were treated with polihexanide eye drops as part of a special access program. The main goal was to see how many were cured after treatment, wit…
Sponsor: SIFI SpA • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New hope for rare eye parasite: study compares drug cocktails and steroid timing
Disease control CompletedThis study looked at the best ways to treat a rare but serious eye infection called acanthamoeba keratitis, which is caused by a parasite. 49 people took part. In the first part, they received either one drug or a combination of two drugs. In the second part, they were given ster…
Phase 2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Hope for rare eye infection: polihexanide shows promise in small study
Disease control CompletedThis study looks back at medical records of 40 people with acanthamoeba keratitis, a rare but serious eye infection. All patients received 0.8 mg/ml polihexanide eye drops as part of a compassionate use program. Researchers want to see how many patients were cured, defined as hav…
Sponsor: SIFI SpA • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New eye scanner could sharpen diagnosis of glaucoma and retina diseases
Diagnosis CompletedThis study is testing a new eye imaging device called the VG200D, which uses advanced technology to take detailed pictures of the eye. Researchers want to see if it works as well as a standard device for measuring parts of the eye in people with glaucoma, retina problems, corneal…
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jul 31, 2026 00:00 UTC
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New registry aims to improve corneal transplants with AI
Knowledge-focused CompletedThis study created a nationwide registry to track long-term results of corneal surgeries and diseases. Researchers collected images and data from 19 participants to help understand what makes corneal transplants successful. The goal is to use this information to develop AI that c…
Sponsor: Nitin Vaswani • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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AI eye chatbot matches doctors in taking patient history
Knowledge-focused CompletedThis study tested whether a large language model (like ChatGPT) could collect medical history and suggest eye tests as well as doctors do. 172 patients with non-emergency eye problems took part. The AI's performance was compared to standard care, with senior specialists checking …
Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC