Abdominal aortic aneurysm

This trial tests whether the anesthetic remimazolam keeps blood pressure more stable than the standard drug propofol in adults undergoing surgery to repair an aortic aneurysm. Maintaining steady blood pressure during these procedures helps protect vital organs. Researchers will m…

This pilot study tests whether a three-week inpatient cardiovascular rehabilitation program, started three months after abdominal aortic aneurysm repair, improves cardiorespiratory fitness more than standard post-operative care. Researchers will measure changes in maximal oxygen …

This study tests whether a short, controlled clamping of the aorta before aneurysm surgery can prevent acute kidney injury. About 206 patients will be randomly assigned to receive this preconditioning or standard care. The goal is to see if this simple procedure lowers the risk o…

This study tests a 'Fast-Track' approach for repairing abdominal aortic aneurysms using local anesthesia, small incisions, and avoiding the ICU. The goal is to see if patients can safely go home in less than 48 hours, reducing hospital costs and freeing up beds. About 50 people w…

This study tests a new stent graft device in 100 people with a bulging iliac artery (aneurysm). The device is placed inside the artery to support it and prevent rupture. Researchers will track serious complications like stroke, heart attack, or kidney problems over time to see if…

This study is testing three types of Bentley stent grafts used to repair complex abdominal aortic aneurysms. Researchers will follow 150 adults for 12 months to see how well the grafts work and if there are any side effects. The goal is to improve the safety and success of this m…

This study tests a special silver-coated mesh placed during emergency abdominal surgery to see if it can prevent surgical site infections and incisional hernias. About 110 adults having urgent open abdominal surgery will take part. Researchers will track infection and hernia rate…

This study is testing whether a deep-learning computer model can predict, from a CT scan taken before surgery, which patients will develop a type II endoleak and aneurysm enlargement after endovascular aneurysm repair (EVAR). The model is being developed using data from multiple …

This study explores whether ultrasound can reliably measure aneurysms in the descending thoracic aorta, the part of the main artery that runs through the chest. Researchers will compare ultrasound measurements with standard CT scans in about 60 adults, including some with known a…

This registry will follow 400 people with complex aortic aneurysms who are treated with GORE devices that help keep blood flowing to vital organs. The goal is to see how well the devices work and how safe they are in everyday medical practice. Participants must need at least one …

This study tests whether evolocumab, a drug that lowers 'bad' cholesterol, changes the cells in the wall of an abdominal aortic aneurysm. About 44 people scheduled for aneurysm repair will receive either the drug or a placebo before surgery. Researchers will then compare the tiss…

This study will use special CT scans that track both the heartbeat and breathing to see how a stent graft moves inside the abdominal aorta after aneurysm repair. Twenty-five patients with complex aneurysms will be scanned before surgery, at discharge, and at 6 and 12 months after…

This study will collect data from 1100 people with peripheral artery disease or abdominal aortic aneurysm across six European centers. Researchers will use artificial intelligence to analyze clinical data, blood samples, imaging, and wearable device information to build tools tha…