New pill tested to fight Tough-to-Treat advanced cancers

NCT ID NCT06324357

Recruiting now Disease control Sponsor: Boehringer Ingelheim Source: ClinicalTrials.gov ↗

Summary

This study is testing a new oral drug called zongertinib for adults with advanced HER2-positive cancers that have spread and stopped responding to prior treatments. The main goals are to find the safest and most effective dose of zongertinib when given alone or combined with other cancer drugs, and to see if these treatments can shrink tumors. The trial will enroll about 768 people with advanced breast, stomach, or colorectal cancers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aichi Cancer Center Hospital
NOT_YET_RECRUITING

Aichi, Nagoya, 464-8681, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Asklepios Kliniken GmbH & Co. KGaA
NOT_YET_RECRUITING

Hamburg, 22763, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Avera Cancer Institute
NOT_YET_RECRUITING

Sioux Falls, South Dakota, 57105, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Az.Osp. Universitaria "Ospedali Riuniti"
NOT_YET_RECRUITING

Foggia, 71122, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Baptist Cancer Center - Memphis
NOT_YET_RECRUITING

Memphis, Tennessee, 38120, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHA Bundang Medical Center
RECRUITING

Seongnam-si, 13496, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHU UCL Namur
RECRUITING

Namur, 5000, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
CIO Clara Campal
RECRUITING

Madrid, 28050, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
CTR Eugène Marquis
NOT_YET_RECRUITING

Rennes, 35042, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CTR François Baclesse
NOT_YET_RECRUITING

Caen, 14076, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CTR Georges-François Leclerc
NOT_YET_RECRUITING

Dijon, 21000, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CTR Leon Berard
NOT_YET_RECRUITING

Lyon, 69008, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Centre Hospitalier Universitaire de Liège
TERMINATED

Liège, 4000, Belgium
Cliniques Universitaires Saint-Luc
NOT_YET_RECRUITING

Brussels, 1200, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
Clínica Universidad de Navarra - Madrid
RECRUITING

Madrid, 28022, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Community Health Network
NOT_YET_RECRUITING

Indianapolis, Indiana, 46250, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Dana-Farber Cancer Institute
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Edegem - UNIV UZ Antwerpen
RECRUITING

Edegem, 2650, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ellison Medical Institute
NOT_YET_RECRUITING

Los Angeles, California, 90064, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Evang. Kliniken Essen-Mitte gGmbh
NOT_YET_RECRUITING

Essen, 45136, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fred Hutchinson Cancer Research Center
RECRUITING

Seattle, Washington, 98109, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Freeman Hospital
NOT_YET_RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, 200032, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fundación Jiménez Díaz
RECRUITING

Madrid, 28040, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
H. Lee Moffitt Cancer Center and Research Institute
NOT_YET_RECRUITING

Tampa, Florida, 33612, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
HOP Tenon
NOT_YET_RECRUITING

Paris, 75020, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hakuaikai Sagara Hospital
NOT_YET_RECRUITING

Kagoshima, 892-0833, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, 150081, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Henan Cancer Hospital
RECRUITING

Zhengzhou, 450003, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Clínic de Barcelona
RECRUITING

Barcelona, 08036, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Clínico San Carlos
NOT_YET_RECRUITING

Madrid, 28040, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Duran i Reynals
NOT_YET_RECRUITING

L'Hospitalet de Llobregat, 8906, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital General Universitario Gregorio Marañón
NOT_YET_RECRUITING

Madrid, 28007, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Teresa Herrera
RECRUITING

A Coruña, 15006, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitari Vall D Hebron
RECRUITING

Barcelona, 08035, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario La Paz
RECRUITING

Madrid, 28046, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Virgen De La Macarena
RECRUITING

Seville, 41009, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital del Mar
NOT_YET_RECRUITING

Barcelona, 08003, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Humanitas Istituto Clinico Catanese S.p.A.
NOT_YET_RECRUITING

Misterbianco (CT), 95045, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hôpital Vivalia De Libramont
RECRUITING

Libramont-Chevigny, 6800, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
INS Bergonie
NOT_YET_RECRUITING

Bordeaux, 33076, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
INS Claudius Regaud IUCT-Oncopole
NOT_YET_RECRUITING

Toulouse, 31059, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
INS Paoli-Calmettes
NOT_YET_RECRUITING

Marseille, 13273, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Inova Schar Cancer Institute
NOT_YET_RECRUITING

Fairfax, Virginia, 22031, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Institut Gustave Roussy
NOT_YET_RECRUITING

Villejuif, 94800, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Institut de Cancérologie de Strasbourg
NOT_YET_RECRUITING

Strasbourg, 67200, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Institut de Cancérologie de l'Ouest
NOT_YET_RECRUITING

Saint-Herblain, 44800, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Instituto Valenciano de Oncología
NOT_YET_RECRUITING

Valencia, 46009, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Di Candiolo
NOT_YET_RECRUITING

Candiolo (TO), 10060, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Nazionale IRCCS Tumori Fondazione Pascale
NOT_YET_RECRUITING

Naples, 80131, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Istituto Scientifico Romagnolo
NOT_YET_RECRUITING

Meldola (FC), 47014, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Japanese Foundation for Cancer Research
RECRUITING

Tokyo, Koto-ku, 135-8550, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Jiangsu Province Hospital
RECRUITING

Nanjing, 210029, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Jilin Province Cancer Hospital
RECRUITING

Changchun, 130012, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kanagawa Cancer Center
RECRUITING

Kanagawa, Yokohama, 241-8515, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Korea University Anam Hospital
RECRUITING

Seoul, 2841, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Kyoto University Hospital
RECRUITING

Kyoto, 606-8507, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Massachusetts General Hospital
NOT_YET_RECRUITING

Boston, Massachusetts, 02114, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic - Florida
NOT_YET_RECRUITING

Jacksonville, Florida, 32224, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic, Rochester
NOT_YET_RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic-Arizona
NOT_YET_RECRUITING

Phoenix, Arizona, 85054, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Memorial Sloan-Kettering Cancer Center
NOT_YET_RECRUITING

New York, New York, 10065, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
National Cancer Center Hospital East
RECRUITING

Kashiwa-shi, 277-8577, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Nottingham University Hospitals NHS Trust
NOT_YET_RECRUITING

Nottingham, NG5 1PB, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Osaka International Cancer Institute
RECRUITING

Osaka, 541-8567, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ospedale San Raffaele S.r.l.
RECRUITING

Milan, 20132, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Penn State Milton S. Hershey Medical Center
NOT_YET_RECRUITING

Hershey, Pennsylvania, 17033, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Royal Free Hospital
RECRUITING

London, NW3 2QG, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, 13620, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Seoul National University Hospital
NOT_YET_RECRUITING

Seoul, 3080, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITING

Seoul, 03722, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITING

Seoul, 6591, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sharp Memorial Hospital
NOT_YET_RECRUITING

San Diego, California, 92123, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine
RECRUITING

Hangzhou, 310000, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
St Bartholomew's Hospital
NOT_YET_RECRUITING

London, EC1A 7BE, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
St James's University Hospital
NOT_YET_RECRUITING

Leeds, LS9 7TF, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tennessee Oncology, Pllc
RECRUITING

Nashville, Tennessee, 37203, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Catholic University of Korea, Seoul St.Mary's Hospital
NOT_YET_RECRUITING

Seoul, 6273, South Korea

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Christie
RECRUITING

Manchester, M20 4BX, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
The First Hospital of Jilin University
NOT_YET_RECRUITING

Changchun, 130021, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Methodist Hospital Research Institute
NOT_YET_RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Oncology Institute of Hope and Innovation
NOT_YET_RECRUITING

Cerritos, California, 90703, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Royal Marsden Hospital, Sutton
NOT_YET_RECRUITING

Sutton, SM2 5PT, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tianjin Cancer Hospital
RECRUITING

Tianjin, 300060, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tokai University Hospital
NOT_YET_RECRUITING

Isehara, 259-1193, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
UZ Leuven
RECRUITING

Leuven, 3000, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
University College Hospital
RECRUITING

London, NW1 2PG, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of California Irvine
RECRUITING

Orange, California, 92868, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of California Los Angeles
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Iowa Hospitals and Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Carl Gustav Carus Dresden
NOT_YET_RECRUITING

Dresden, 01307, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Erlangen
NOT_YET_RECRUITING

Erlangen, 91054, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Mannheim GmbH
NOT_YET_RECRUITING

Mannheim, 68167, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Ulm
NOT_YET_RECRUITING

Ulm, 89075, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Valkyrie Clinical Trials
RECRUITING

Los Angeles, California, 90067, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Velindre Cancer Centre
NOT_YET_RECRUITING

Cardiff, CF14 2TL, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Virginia Cancer Specialists, PC
RECRUITING

Fairfax, Virginia, 22031, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06510, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

COLORECTAL CANCER ESOPHAGEAL ADENOCARCINOMA GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA METASTATIC BREAST CANCER METASTATIC GASTRIC ADENOCARCINOMA