Bone drug injection may help dental anchors last longer
NCT ID NCT07546058
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether injecting a small amount of zoledronic acid near orthodontic miniscrews helps them stay in place. Sixty-eight patients each received the drug on one side of the mouth and a placebo on the other. The goal was to see if the drug reduces screw loosening and inflammation over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- zoledronic acid (a bisphosphonate drug)
- What this could lead to
- If it works, this could offer a simple way to prevent orthodontic miniscrews from loosening, improving treatment outcomes.
- What could go wrong
- This is a small, completed trial with 68 patients. The drug's local use is experimental, and long-term safety or effectiveness in broader populations is unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Latakia University
Latakia, Latakia Governorate, Syria
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