Can zinc strengthen bones in sickle cell disease? new study seeks answers
NCT ID NCT06260891
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two daily doses of zinc (25 mg and 40 mg) in 34 adults with sickle cell disease to see which dose works best for bone health. Participants take zinc for 12 weeks, and researchers measure changes in bone formation and breakdown markers. The goal is to pick the right dose for a future larger trial on zinc and bone health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
zinc (as zinc gluconate)
What this could lead to
If successful, this study could determine the best zinc dose for a larger trial aiming to improve bone health in people with sickle cell disease.
What could go wrong
This is a small, early-phase study focused on finding the right dose and measuring bone markers, not on treating the disease itself. Results may not lead to a proven treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor College of Medicine
NOT_YET_RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
Contact
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Children's Hospital of Philadelphia
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Email: •••••@•••••
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Cincinnati Children's Hospital
NOT_YET_RECRUITINGCincinnati, Ohio, 45229, United States
Contact Email: •••••@•••••
Contact
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Duke University Medical Center
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
Contact
Contact Email: •••••@•••••
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Thomas Jefferson University Hospital
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
Contact
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UCSF Benioff Children's Hospital Oakland
RECRUITINGOakland, California, 94609, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••