Simple zinc pill may shield kids with sickle cell from deadly infections

NCT ID NCT06561061

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether daily zinc supplements can lower the number of serious infections in young children with sickle cell anemia. Researchers in Uganda gave 100 children either zinc or a placebo for a period and tracked infections. The goal is to find an affordable, easy-to-use way to protect these children from life-threatening illnesses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

zinc sulfate

What this could lead to

If zinc proves effective, it could offer a simple, low-cost way to reduce dangerous infections in children with sickle cell disease.

What could go wrong

This is a completed Phase 2/3 trial with only 100 children in Uganda, so results may not apply to other populations. Zinc may not reduce infections enough to change practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sickle cell disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jinja Hospital

    Jinja, Uganda