Simple combo may shield cancer patients from debilitating skin side effect
NCT ID NCT06856590
First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 33 times
Summary
This study tested whether taking zinc supplements and applying a strong steroid cream (clobetasol) can prevent or lessen hand-foot skin reaction—a painful rash on palms and soles—caused by the cancer drug regorafenib. About 150 adults starting regorafenib for various cancers were split into three groups: zinc plus cream, cream alone, or zinc alone. Researchers tracked skin reactions and quality of life over 8 weeks to see which approach works best.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Afyonkarahisar University of Health Sciences Hospital
Afyonkarahisar, 03030, Turkey (Türkiye)
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Ankara Etlik City Hospital
Ankara, Yenimahalle, 06170, Turkey (Türkiye)
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Ankara University Faculty of Medicine Hospital
Ankara, 06230, Turkey (Türkiye)
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Bursa Uludağ University Hospital
Bursa, Nilüfer, 16059, Turkey (Türkiye)
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Dicle University Hospital
Diyarbakır, 21280, Turkey (Türkiye)
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Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Ankara, Yenimahalle, 06200, Turkey (Türkiye)
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Gazi University
Ankara, Yenimahalle, 06500, Turkey (Türkiye)
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Hacettepe University Faculty of Medicine Hospital
Ankara, 06230, Turkey (Türkiye)
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Karadeniz Technical University Hospital
Trabzon, Ortahisar, 61080, Turkey (Türkiye)
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Necmettin Erbakan University Meram Faculty of Medicine Hospital
Konya, Meram, 42080, Turkey (Türkiye)
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Sakarya University Hospital
Sakarya, Serdivan, 54050, Turkey (Türkiye)
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Tekirdağ Namık Kemal University Hospital
Tekirdağ, 59100, Turkey (Türkiye)
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Van Yüzüncü Yıl University Dursun Odabaş Hospital
Van, 65080, Turkey (Türkiye)
Conditions
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