Lung valve registry shows promise for emphysema patients

NCT ID NCT04517916

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed French registry tracked 155 adults with severe emphysema or COPD who received Zephyr Valves, tiny devices placed in the lungs to help them work better. The goal was to see if the treatment safely improves breathing over 12 months. Researchers measured lung function and used CT scans to check for lung volume reduction.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Zephyr Valve (a device placed in the lungs to reduce air trapping)

What this could lead to

If results are positive, this could support continued use of the Zephyr Valve as a safe and effective treatment for severe emphysema/COPD.

What could go wrong

This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients, and risks like infection or valve movement exist.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Arnaud de Villeneuve

    Montpellier, France

  • Hôpital Bichat

    Paris, France

  • Hôpital Calmette

    Lille, France

  • Hôpital Charles Nicolle

    Rouen, France

  • Hôpital Cochin

    Paris, France

  • Hôpital Dupuytren

    Limoges, France

  • Hôpital François Mitterrand

    Dijon, France

  • Hôpital La Cavale Blanche

    Brest, France

  • Hôpital Larrey

    Toulouse, France

  • Hôpital Nord

    Latronche, France

  • Hôpital Nord

    Saint-Etienne, France

  • Nouvel Hôpital Civil

    Strasbourg, France