New combo therapy for tough breast cancer shows promise, but trial halted early
NCT ID NCT03901469
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 31 times
Summary
This study tested a combination of two drugs, ZEN003694 and talazoparib, in people with triple-negative breast cancer who do not have BRCA gene mutations. The goal was to see if the combination could shrink tumors or slow the disease. The trial was terminated early, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Affliated Hospital of Jining Medical University
Jining, Shandong, 272000, China
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Banner MD Anderson Cancer Center
Gilbert, Arizona, 85234, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Emory University Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Hunan Cancer Hospital
Changsha, Hunan, 410000, China
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Institut Jules Bordet
Anderlecht, 1070, Belgium
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MD Anderson
Houston, Texas, 77030, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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START Madrid
Madrid, 28050, Spain
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, 510289, China
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510060, China
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Tennessee Oncology (Sarah Cannon)
Nashville, Tennessee, 37203, United States
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The First Affiliated Hosptial of Bengbu Medical College
Bengbu, Anhui, 233000, China
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The Second People's Hospital of Neijiang
Neijiang, Sichuan, 641100, China
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Tianjing Medical University Cancer Institute & Hospital
Tianjin, Tianjin Municipality, 300060, China
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UZ Leuven
Leuven, 3000, Belgium
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University of Kansas Cancer Center
Westwood, Kansas, 66203, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Vall d'Hebron Institute of Oncology (VHIO)
Barcelona, 08035, Spain
Conditions
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