New drug combo aims to shrink Hard-to-Treat cancers
NCT ID NCT05803382
First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 30 times
Summary
This early-stage trial tests whether adding an experimental drug (ZEN003694) to a standard chemotherapy (capecitabine) is safe and tolerable for people with advanced solid tumors that have spread or can't be removed by surgery. About 30 adults whose cancer has worsened after standard treatments will receive the combination. The main goals are to find the best dose and check for side effects.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Memorial Hospital East
ACTIVE_NOT_RECRUITINGShiloh, Illinois, 62269, United States
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Montefiore Medical Center - Moses Campus
RECRUITINGThe Bronx, New York, 10467, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Montefiore Medical Center-Einstein Campus
RECRUITINGThe Bronx, New York, 10461, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Montefiore Medical Center-Weiler Hospital
RECRUITINGThe Bronx, New York, 10461, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
ACTIVE_NOT_RECRUITINGNew York, New York, 10032, United States
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Siteman Cancer Center at Christian Hospital
ACTIVE_NOT_RECRUITINGSt Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
ACTIVE_NOT_RECRUITINGCity of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
ACTIVE_NOT_RECRUITINGCreve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
ACTIVE_NOT_RECRUITINGSt Louis, Missouri, 63129, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITINGOrange, California, 92868, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITINGIrvine, California, 92612, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UF Health Cancer Institute - Gainesville
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Cincinnati Cancer Center-West Chester
RECRUITINGWest Chester, Ohio, 45069, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Clinical Research Center
RECRUITINGFairway, Kansas, 66205, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
Contact
Contact Phone: •••-•••-••••
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Vanderbilt Breast Center at One Hundred Oaks
RECRUITINGNashville, Tennessee, 37204, United States
Contact Phone: •••-•••-••••
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Vanderbilt University/Ingram Cancer Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-••••
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Washington University School of Medicine
ACTIVE_NOT_RECRUITINGSt Louis, Missouri, 63110, United States
Conditions
Explore the condition pages connected to this study.