Can a new pill tame childhood cancers that Won't quit?
NCT ID NCT07773454
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This early-stage trial is testing an experimental drug called zanzalintinib in children and teens with solid tumors that have returned or not responded to standard treatment. The main goals are to find the highest safe dose and to see how well the drug is tolerated. Participants receive the drug and are closely monitored for side effects and how the drug moves through their bodies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- zanzalintinib (also known as XL092), an oral drug being tested for its safety and tolerability in children with certain cancers
- What this could lead to
- If successful, this could establish a safe dose of zanzalintinib for children and potentially offer a new treatment option for hard-to-treat pediatric solid tumors.
- What could go wrong
- This is an early-phase trial with a small number of participants, so the drug may not prove effective or may cause significant side effects. The results will only guide further study, not confirm a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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