Exelixis

This is the first human study of a new experimental drug called XB628, designed to help the immune system fight cancer. The trial will test different doses of the drug in 75 people with advanced solid tumors that have returned or spread after previous treatments. The main goals a…

This early-stage study is testing a new drug called XB371 in people with advanced solid tumors that have spread or returned after treatment. Researchers want to find the safest dose, check for side effects, and see how the body processes the medication. The study will enroll abou…

This is the first human study of an experimental cancer drug called XL309. Researchers are testing it alone and combined with another cancer drug (olaparib) in 429 patients with advanced solid tumors that have stopped responding to standard treatments. The main goals are to deter…

This study is testing a new drug called XL092, both by itself and in combination with other immunotherapy drugs, for people with advanced solid tumors that cannot be removed by surgery. The main goals are to find safe doses and see if the treatments can shrink tumors or slow thei…

This study is testing whether a new drug called zanzalintinib works better than the current standard drug everolimus for people with advanced neuroendocrine tumors that have grown despite previous treatments. The trial will enroll 440 participants whose cancer cannot be surgicall…

This is the first study in people to test a new drug called XB010 for advanced solid tumors. The main goals are to find a safe dose and see how the body handles the drug, both by itself and when combined with another cancer therapy. It is for adults with certain advanced cancers …