New hope for advanced cancers: first human trial of XL309 begins
NCT ID NCT05932862
First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 28 times
Summary
This study tests a new drug called XL309, alone or with another drug (olaparib), in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. About 429 adults will take part in this early-phase trial.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Exelixis Clinical Site #1
RECRUITINGHouston, Texas, 77030, United States
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Exelixis Clinical Site #10
WITHDRAWNKansas City, Missouri, 64111, United States
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Exelixis Clinical Site #11
RECRUITINGGermantown, Tennessee, 38138, United States
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Exelixis Clinical Site #12
WITHDRAWNFountain Valley, California, 92708, United States
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Exelixis Clinical Site #13
RECRUITINGOklahoma City, Oklahoma, 73104, United States
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Exelixis Clinical Site #14
RECRUITINGRochester, Minnesota, 55905, United States
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Exelixis Clinical Site #15
RECRUITINGJacksonville, Florida, 32224, United States
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Exelixis Clinical Site #16
RECRUITINGTampa, Florida, 33612, United States
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Exelixis Clinical Site #2
WITHDRAWNHouston, Texas, 77030, United States
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Exelixis Clinical Site #3
RECRUITINGSan Antonio, Texas, 78229, United States
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Exelixis Clinical Site #4
RECRUITINGAustin, Texas, 78758, United States
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Exelixis Clinical Site #5
RECRUITINGNew York, New York, 10029, United States
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Exelixis Clinical Site #6
RECRUITINGNashville, Tennessee, 37203, United States
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Exelixis Clinical Site #7
RECRUITINGCleveland, Ohio, 44106, United States
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Exelixis Clinical Site #8
RECRUITINGOrlando, Florida, 32827, United States
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Exelixis Clinical Site #9
RECRUITINGNew Brunswick, New Jersey, 08901, United States
Conditions
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