Targeted drug shows promise for multiple Hard-to-Treat cancers

NCT ID NCT07192068

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 33 times

Summary

This study tests a drug called zanidatamab in adults whose cancers have a specific change in the HER2 gene. It includes people with lung, colorectal, endometrial, head and neck, or sarcoma cancers that have not responded to other treatments. The main goal is to see if the drug can shrink tumors. Participants receive the drug by IV every three weeks and are monitored regularly for side effects and disease changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Chu Timone

    RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Gustave Roussy

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de Lorraine

    ACTIVE_NOT_RECRUITING

    Vandœuvre-lès-Nancy, France

  • Institut de Cancérologie de l'Ouest

    ACTIVE_NOT_RECRUITING

    Angers, France

Conditions

Explore the condition pages connected to this study.