New pill takes aim at Hard-to-Treat cancers
NCT ID NCT06209385
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This early-phase trial tests an experimental tablet called YZJ-5053 in people with advanced solid tumors who have no standard treatment options left. The main goals are to find a safe dose and check for side effects. Researchers will also look at how the drug moves through the body and whether it can shrink tumors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
YZJ-5053 (also called SHY-1901) tablets
What this could lead to
If safe and effective, this could lead to a new oral treatment option for people with advanced solid tumors who have run out of standard therapies.
What could go wrong
This is a very early, small Phase 1 trial focused on safety and dosing, not proof of effectiveness. The drug may cause side effects or fail to shrink tumors.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shandong Cancer Hospital
Jinan, Shandong, 250000, China
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Shanghai East Hospital
Shanghai, Shanghai Municipality, 200120, China
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330000, China
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The Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China