New combo therapy aims to shrink untreatable liver tumors

NCT ID NCT07334483

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether a combination of radioactive beads (yttrium-90), an immunotherapy drug (camrelizumab), and a targeted therapy (apatinib) works better than standard chemoembolization for liver cancer that cannot be surgically removed. About 120 adults with non-metastatic liver cancer will be randomly assigned to different treatment groups. The main goal is to see how many patients' tumors shrink significantly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Yttrium-90 microspheres (radioactive beads), camrelizumab (immunotherapy), apatinib (targeted therapy)

What this could lead to

If successful, this could offer a more effective treatment option for people with liver cancer that cannot be removed by surgery, potentially shrinking tumors better than current standard therapy.

What could go wrong

This is a mid-stage trial with only 120 participants, so results may not apply to everyone. Combining treatments also raises the risk of side effects like liver damage or immune reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tsinghua Changgung Hospital

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanjing Tianyinshan Hospital

    NOT_YET_RECRUITING

    Nanjin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhongshan Hospital Fudan University

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••