Can a One-Time radiation bead treatment extend life in advanced liver cancer?

NCT ID NCT06166576

Recruiting now Disease control Sponsor: Seoul National University Hospital Source: ClinicalTrials.gov ↗

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial is testing a procedure called ablative radioembolization, which delivers tiny radioactive beads (Yttrium-90) directly to liver tumors. It is for adults with hepatocellular carcinoma that has spread into the portal vein but is still confined to one lobe of the liver. The goal is to see if this high-dose radiation approach can improve overall survival and shrink tumors in people who maintain good liver function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Yttrium-90 glass microspheres (TheraSphere) given via ablative radioembolization
What this could lead to: If successful, this could offer a more effective way to treat liver cancer that has spread into nearby blood vessels, potentially extending survival.
What could go wrong: This is a small, early-phase study, so results may not apply broadly. The high radiation dose could damage healthy liver tissue or cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA

Contacts and locations

Locations

National Cancer Center
RECRUITING

Ilsan, Gyeonggi-do, 10408, South Korea
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul, 03080, South Korea
Severance Hospital
RECRUITING

Seoul, 03722, South Korea

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