Can a single radiation dose cure large liver tumors?

This trial is testing a high-dose radiation treatment called Yttrium-90 radioembolization for people with large hepatocellular carcinoma (a type of liver cancer) that is larger than 8 cm. The treatment delivers tiny radioactive beads directly to the tumor's blood supply, aiming to destroy it. The goal is to see if this approach can cure the cancer or shrink it enough to allow surgery. The study involves about 30 adults with good liver function and no spread of cancer outside the liver.