Could a sweetener stop deadly infections in transplant kids?

NCT ID NCT05579639

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special wipe containing xylitol, a natural sweetener, can reduce dangerous bloodstream infections in children and young adults undergoing stem cell transplants. These infections often start from bacteria in the mouth and can be life-threatening. Participants will be randomly assigned to receive either the xylitol wipe or a placebo wipe twice daily during their hospital stay.

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Conditions

The condition(s) this trial relates to.

gingivitis mucositis Plaque, Amyloid Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Dana-Farber/Boston Children's

    Boston, Massachusetts, 02115, United States

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