New drug trial aims to keep blood cancers at bay after transplant

NCT ID NCT03286530

Summary

This study is testing whether taking the drug ruxolitinib after a stem cell transplant can help prevent cancer from returning in older patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). The trial involves 64 participants aged 60-80 who have achieved remission and will receive a stem cell transplant. Researchers want to see if ruxolitinib, taken as ongoing maintenance therapy, improves survival by reducing both cancer relapse and transplant complications.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

  • Medical College of Wisconsin

    Wauwatosa, Wisconsin, 53226, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • Vanderbilt University

    Nashville, Tennessee, 37235, United States

  • Washington University

    St Louis, Missouri, 63130, United States

Conditions

Explore the condition pages connected to this study.