New drug XYA02 takes on tough cancers in first human trial
NCT ID NCT07670312
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study tests a new biologic drug called XYA02 in 190 adults with advanced solid tumors (including lung, ovarian, and pancreatic cancers) that have not responded to standard treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. It is an early-stage trial, so the results will help decide if larger studies are warranted.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- XYA02 (a biologic given by IV infusion)
- What this could lead to
- If successful, this could point toward a new treatment option for people with advanced solid tumors that have stopped responding to other therapies.
- What could go wrong
- This is an early-phase trial (Phase 1b/2) with a small number of participants, so the drug may not prove effective or safe enough for wider use. Side effects are unknown at this stage.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Chris O'Brien Life House
Sydney, New South Wales, Australia
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Linear Clinical Research
Perth, Western Australia, Australia
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Monash Medical Centre
Melbourne, Victoria, Australia
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Peter MacCallum Cancer Centre
Melbourne, Victoria, Australia
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Westmead Hospital
Sydney, New South Wales, Australia
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