Experimental drug XmAb27564 tested for skin conditions – trial halted early

NCT ID NCT06005792

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested an experimental drug called XmAb27564 in 23 people with mild-to-severe plaque psoriasis or moderate-to-severe atopic dermatitis. Participants received four doses of the drug or a placebo every two weeks. The main goal was to check safety and tolerability. The study was terminated, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

XmAb27564

What this could lead to

If successful, this could point toward a new treatment option for plaque psoriasis and atopic dermatitis.

What could go wrong

This was a very early (Phase 1) trial that was terminated, so results are limited. The drug may not prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Clinical Studies, LTD. LLP

    Webster, Texas, 77598, United States

  • Clinical Trials Research Institute

    Thousand Oaks, California, 91320, United States

  • Driven Research

    Coral Gables, Florida, 33134, United States

  • Innovaderm Research Inc.

    Montreal, Quebec, H2X 2V1, Canada

  • J&S Studies, Inc

    College Station, Texas, 77845, United States

  • San Marcus Research Clinic

    Miami Lakes, Florida, 33104, United States

  • Unison Clinical Trials

    Sherman Oaks, California, 91403, United States