Xencor, Inc.

This early-stage study is testing the safety and side effects of a new drug called plamotamab in adults with moderate to severe rheumatoid arthritis. About 47 participants who haven't responded well to standard arthritis medications will receive injections of the drug at differen…

This is the first study in humans to test the safety and find the right dose of a new drug called XmAb541 for people with advanced solid tumors, including ovarian, endometrial, and germ cell cancers. The main goal is to see how well the drug is tolerated and to check for side eff…

This study is testing a new drug called XmAb942 to see if it is safe and can help control ulcerative colitis (UC). The first part checks safety in healthy people, and the second part tests if the drug reduces disease activity in people with moderate-to-severe UC. Participants wit…

This early-stage study is testing a new drug called XmAb819 in people with advanced kidney cancer that has returned or stopped responding to standard treatments. The main goal is to find safe dose levels and check for side effects when the drug is given through an IV or injection…