Breathing in xenon: a new MRI scan to see lung damage?
NCT ID NCT05241275
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study at Duke University tests whether a special MRI scan using inhaled xenon gas can detect changes in lung function over time in people with progressive pulmonary fibrosis. Sixty adults with various types of lung scarring will have MRI scans before starting anti-fibrotic medication and again at 3, 6, and 12 months. The goal is to see if this imaging method can measure how the lungs respond to treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyperpolarized 129 Xenon gas (used as an imaging agent for MRI)
What this could lead to
If successful, this could provide a new way to monitor lung disease progression and treatment response without invasive tests.
What could go wrong
This is a small, early-phase study (60 people) at one center. The imaging technique is experimental and may not prove reliable or widely usable.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University
Durham, North Carolina, 27710, United States