Sound waves could unlock the minds of Brain-Injured patients
NCT ID NCT06693492
First seen Feb 17, 2026 · Last updated Jun 22, 2026 · Updated 16 times
Summary
This study tests whether ultrasound can help doctors better understand and treat people with disorders of consciousness, like coma or a minimally conscious state, after severe brain injury. Researchers will use ultrasound to look at brain structure and function, and also try low-intensity focused ultrasound as a treatment. The goal is to find a cheaper, more accessible way to diagnose and help these patients, who are often difficult to assess with standard methods.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fondazione IRCCS Istituto Neurologico C. Besta, Neurology, Public Helath, Disability Unit
RECRUITINGMilan, Lombardy, 20133, Italy
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Centro Neurolesi Bonino Pulejo, Neuroimaging Lab
RECRUITINGMessina, Sicily, 98124, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS Istituto delle Scienze Neurologiche di Bologna, UO di Medicina Riabilitativa e Neuroriabilitazione
RECRUITINGBologna, Emilia-Romagna, 40139, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Istituto S. Anna, Semi-Intensive Rehabilitation Unit for Acquired Brain Injury
RECRUITINGCrotone, Calabria, 88900, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ultrasound (diagnostic and therapeutic)
What this could lead to
If successful, this could lead to a low-cost, bedside tool to better diagnose and treat patients with disorders of consciousness.
What could go wrong
This is an early exploratory study with no phase, so results may not change practice. The treatment effect of ultrasound stimulation is uncertain.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.