Can a weekly pill stop STIs? new study tests doxycycline in kenyan women
NCT ID NCT06582966
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether taking doxycycline once a week can prevent bacterial sexually transmitted infections (STIs) in cisgender women who are already taking HIV PrEP. Sixty women in Kisumu, Kenya, received the antibiotic weekly under direct observation for six months. The main goal was to see how well they stuck to the regimen and whether they found it acceptable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
doxycycline
What this could lead to
If successful, this could point toward a simple weekly pill to help prevent bacterial STIs in women at risk.
What could go wrong
This is a small pilot study with only 60 participants and no control group, so results may not apply broadly. Adherence and side effects could limit effectiveness.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kenya Medical Research Institute -KEMRI
Kisumu, Kenya