Can a weekly pill stop STIs? new study tests doxycycline in kenyan women
NCT ID NCT06582966
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether taking doxycycline once a week can prevent bacterial sexually transmitted infections (STIs) in cisgender women who are already taking HIV PrEP. Sixty women in Kisumu, Kenya, received the antibiotic weekly under direct observation for six months. The main goal was to see how well they stuck to the regimen and whether they found it acceptable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- doxycycline
- What this could lead to
- If successful, this could point toward a simple weekly pill to help prevent bacterial STIs in women at risk.
- What could go wrong
- This is a small pilot study with only 60 participants and no control group, so results may not apply broadly. Adherence and side effects could limit effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STI are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kenya Medical Research Institute -KEMRI
Kisumu, Kenya
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A simple survey may curb teen drinking and HIV risk — a trial puts it to the test
- Banking on health: savings accounts may cut HIV risk in kenyan men
- App and coaching help men stick with HIV prevention pill
- Hidden STI threat: antibiotic-resistant bug found in HIV-positive men
- Could a simple STI test prevent preterm birth?
- Survivor-Made messages aim to increase HIV testing and overdose kit use