A 20-Minute walk: a new way to boost brain health in MS?

NCT ID NCT06233370

Ongoing Knowledge-focused Sponsor: Kessler Foundation Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study explores whether a brief, moderate-intensity walk can alter brain function and blood flow in people with multiple sclerosis. Participants will undergo MRI scans before and after either treadmill or overground walking at a brisk pace. The goal is to see if even a single session of exercise can produce measurable changes in the brain, which could inform future strategies for managing MS symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Moderate intensity walking exercise (treadmill or overground) at a pace of about 100 steps per minute
What this could lead to: If a single bout of walking measurably alters brain function and blood flow, it could point toward exercise as a way to support brain health in multiple sclerosis.
What could go wrong: This is a small, early-phase study focused on immediate brain changes, not long-term outcomes. Results may not translate to lasting benefits or apply to all people with MS.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

Kessler Foundation

West Orange, New Jersey, 07052, United States

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