New vaccine combo aims to supercharge immune attack on breast cancer
NCT ID NCT03632941
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding a HER2-targeting vaccine (VRP-HER2) to the immunotherapy drug pembrolizumab could boost the immune system's attack on advanced HER2-positive breast cancer. Eight participants were randomly assigned to receive the vaccine alone, pembrolizumab alone, or both together. The main goal was to see if the combination increased T-cell activity against the cancer, while also monitoring safety.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Duke University
Durham, North Carolina, 27710, United States