New shot for bulging eyes shows promise in early trial
NCT ID NCT07155668
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a new drug called VRDN-003 in 87 people with thyroid eye disease (TED). The drug is given as a shot under the skin and targets a protein linked to the disease. The main goal was to check safety and how the drug moves through the body, not yet to measure how well it treats symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
VRDN-003 (a monoclonal antibody targeting IGF-1 receptor)
What this could lead to
If successful, this could lead to a new treatment option for thyroid eye disease that is given as a simple injection under the skin.
What could go wrong
This is an early-phase study focused on safety and drug levels, not yet on how well it works. The drug may not prove effective in larger trials or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Quality Medical Research, LLC
Orland Park, Illinois, 60462, United States
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Baylor College of Medicine, Alkek Eye Center
Houston, Texas, 77030, United States
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C&A Clinical Trials Corp
Cape Coral, Florida, 33990, United States
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Continental Clinical Research, llc
Miami, Florida, 33144, United States
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Fraser Eye Center
Fraser, Michigan, 48026, United States
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Hype Clinical Research, LLC
Miami, Florida, 33145, United States
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Ilumina Medical Research
Kissimmee, Florida, 34744, United States
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Kahana Oculoplastic and Orbital Surgery
Livonia, Michigan, 48152, United States
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Med-Care Research
Miami, Florida, 33125, United States
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Neuro Eye Clinical Trials INC
Houston, Texas, 77074, United States
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Ophthalmic Consultants of Boston
East Weymouth, Massachusetts, 02189, United States
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United Medical Research Institute
Inglewood, California, 90301, United States
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Vector Clinical Trials
Sparks, Nevada, 89128, United States