Could a common acid blocker save transplanted kidneys?

NCT ID NCT07275632

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests whether a stomach acid drug called vonoprazan fumarate can reduce delayed graft function, a common complication where a new kidney doesn't work right away. About 47 first-time kidney transplant recipients will take the drug for seven days after surgery. Researchers will measure how many need dialysis and how well the kidney recovers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vonoprazan fumarate

What this could lead to

If it works, this could point toward a simple, short-term treatment to help new kidneys work sooner after transplant, reducing the need for dialysis.

What could go wrong

This is a very early, small study (47 people) with no placebo group, so results may not be reliable. The drug may not work or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Delayed Graft Function end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    NOT_YET_RECRUITING

    Guangzhou, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••