New drug trial targets debilitating itch in liver disease patients

NCT ID NCT05050136

Recruiting now Symptom relief Sponsor: Mirum Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an experimental drug called volixibat can reduce severe itching in people with primary biliary cholangitis (PBC), a chronic liver disease. Researchers will compare volixibat against a placebo in 260 adult participants to see if it safely improves itch severity and quality of life. The study will also monitor whether the drug affects the underlying liver disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

(G.I.R.I.) GI Research Institute Foundation
RECRUITING

Vancouver, British Columbia, V6Z 2K5, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
ASST Grande Ospedale Metropolitano Niguarda
RECRUITING

Milan, 20162, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
ASST Papa Giovanni XXIII
RECRUITING

Bergamo, 24127, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Advanced Research Institute, Inc
RECRUITING

New Port Richey, Florida, 34653, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Amel Med LLC
TERMINATED

Austin, Texas, 78750, United States
Amstedam University Medical Centers
RECRUITING

Amsterdam, 1081 HV, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
Azienda Ospedale-Università di Padova
RECRUITING

Padua, 35128, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
RECRUITING

Palermo, 90127, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Azienda Ospedaliero Universitaria Di Modena
RECRUITING

Modena, 41126, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Azienda Ospedaliero Universitaria Pisana (AOUP)
RECRUITING

Pisa, 56124, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, 10050, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Beijing Youan Hospital, Capital Medical University
RECRUITING

Beijing, 100069, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Belfast Health & Social Care Trust (BHSCT) Royal Victoria Hospital
RECRUITING

Belfast, BT12 6BA, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Beth Israel Deaconess
RECRUITING

Boston, Massachusetts, 02215, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Bon Secours Liver Institute of Hampton Roads Mary Immaculate Hospital
RECRUITING

Newport News, Virginia, 23602, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Bon Secours Richmond Community Hospital LLC d/b/a Bon Secours Liver Institute of Richmond
RECRUITING

Richmond, Virginia, 23226, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHI Health Clinic (Alegent Creighton Clinic)- Gastroenterology-Bergan
RECRUITING

Omaha, Nebraska, 68124, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHU Grenoble - Hôpital MICHALLON
RECRUITING

Grenoble, 38043, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CHU de NICE- Hospital L'Archet 2
RECRUITING

Nice, 06202, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
CRCHUM (Centre de Recherche du Centre Hospitalier de l'Université de Montréal)
RECRUITING

Montreal, H2X 0A9, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
Carmel Medical Center
RECRUITING

Haifa, 3434104, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cedars Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Centro de Pesquisa Clínica da Bahiana Saúde
RECRUITING

Salvador, Estado de Bahia, 40290-000, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Centro de Pesquisas Clínicas do HC/UFMG-EBSERH
RECRUITING

Belo Horizonte, Minas Gerais, 30130-100, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cleveland Clinic - Main Campus
RECRUITING

Cleveland, Ohio, 44195, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Cliniques Universitaires Saint-Luc
RECRUITING

Brussels, 1200, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
Clínica de Nefrología, Urología y Enfermedades Cardiovasculares
RECRUITING

Santa Fe, 3000, Argentina

Contact Phone: •••-•••-•••• Email: •••••@•••••
Covenant Metabolic Specialists
TERMINATED

Fort Myers, Florida, 33912, United States
Covenant Research and Clinics, LLC
TERMINATED

Sarasota, Florida, 34240, United States
Ehime University Hospital
RECRUITING

Ehime, 791-0295, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Einstein Healthcare Network - Einstein Medical Center
RECRUITING

Philadelphia, Pennsylvania, 19141, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ente Ospedaliero Cantonale
RECRUITING

Lugano, 6900, Switzerland

Contact Phone: •••-•••-•••• Email: •••••@•••••
Erasmus medical center
RECRUITING

Rotterdam, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fondazione Ca Granda
RECRUITING

Milan, 20122, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fondazione IRCCS San Gerardo dei Tintori
RECRUITING

Monza, 20900, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Fundação Oswaldo Ramos
RECRUITING

São Paulo, 04038-002, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Galen Medical Group, P.C
RECRUITING

Tennessee City, Tennessee, 37343, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-••••
Galilee Medical Center
RECRUITING

Nahariya, 2210001, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••
Glenny Corp S.A
RECRUITING

CABA, 1430, Argentina

Contact Phone: •••-•••-•••• Email: •••••@•••••
Gordon and Leslie Diamond Health Care Centre, Division of Gastroenterology
RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hadassah Medical Center - Ein Karem, Liver Institute Kiryat Hadassah POB 12000
RECRUITING

Jerusalem, 9112001, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hillel Yaffe Medical Center
TERMINATED

Hadera, 3810101, Israel
Hopital Claude Huriez-Digestive system disease clinic
RECRUITING

Lille, 59037, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Clínic de Barcelona
RECRUITING

Barcelona, 08036, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Das Clínicas Da Ufg
RECRUITING

Goiânia, Goiás, 74605-050, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, 28007, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Paul Brousse- APHP
RECRUITING

Villejuif, 94800, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Provincial Del Centenario
RECRUITING

Rosario, Santa Fe Province, 2000, Argentina

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Saint Antoine
RECRUITING

Paris, 75012, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitari Parc Tauli
RECRUITING

Barcelona, 08208, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitari Vall d' Hebron
RECRUITING

Barcelona, 08035, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Miguel Servet
RECRUITING

Zaragoza, 50009, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital de Alta Complejidad En Red El Cruce
RECRUITING

San Juan Bautista, Buenos Aires, 1888, Argentina

Contact Phone: •••-•••-•••• Email: •••••@•••••
Hospital de Clínicas de Porto Alegre
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035903, Brazil

Contact Phone: •••-•••-•••• Email: •••••@•••••
IHS Health
TERMINATED

Kissimmee, Florida, 34741, United States
Impact Research
TERMINATED

Waco, Texas, 76710, United States
Istituto Clinico Humanitas
RECRUITING

Rozzano, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Jackson Liver and GI Specialists
TERMINATED

Jackson, Mississippi, 39216, United States
King's College Hospital NHS Foundation Trust
RECRUITING

London, SE5 9RS, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Klinikum Chemnitz gGmbH
RECRUITING

Chemnitz, 09116, Germany

Contact Phone: •••-•••-••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
LSU Health Science Center Shreveport
RECRUITING

Shreveport, Louisiana, 71103, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Liver Associates of Texas
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Liver Institute Northwest
RECRUITING

Seattle, Washington, 98105, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Loyola University Health System - Loyola Outpatient Center
RECRUITING

Maywood, Illinois, 60153, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
McGill University Health Centre
RECRUITING

Montreal, Quebec, H4A 3J1, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
McMaster University Medical Center
RECRUITING

Hamilton, Ontario, L8S 4K1, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
MedStar Health Research Institute
RECRUITING

Fairfax, Virginia, 22031, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Medizinische Hochschule Hannover (MHH)
RECRUITING

Hanover, 30625, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mengchao Hepatobiliary Hospital of Fujian Medical University
RECRUITING

Fuzhou, Fujian, 350028, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Methodist Le Bonheur Healthcare
TERMINATED

Memphis, Tennessee, 38104, United States
National Hospital Organization Nagasaki Medical Center
RECRUITING

Ōmura, Nagasaki, 856-8562, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Nottingham University Hospitals NHS Trust
RECRUITING

Nottingham, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Nouvel Hospital Civil
RECRUITING

Strasbourg, 67091, France

Contact Phone: •••-•••-•••• Email: •••••@•••••
Ochsner Clinic Foundation-Baton Rouge
RECRUITING

Baton Rouge, Louisiana, 70836, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Osaka Rosai Hospital
RECRUITING

Osaka, 591-8025, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
Rabin Medical Center
RECRUITING

Petah Tikva, 4941492, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••
Radboudumc
RECRUITING

Nijmegen, 6525 GA, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
Rambam Medical Center
RECRUITING

Haifa, 3109601, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Royal Free Hospital NHS Foundation Trust
RECRUITING

London, NW3 2QZ, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
Schiff Center for Liver Diseases
TERMINATED

Miami, Florida, 33136, United States
Science 37, Inc (Remote-homebased Telemedicine)
RECRUITING

Morrisville, North Carolina, 27560, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Shaare Zedek Medical Center
TERMINATED

Jerusalem, 9103102, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, 52621, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sir Run Run Shaw Hospital -Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310009, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Soma Clinical Trials
TERMINATED

Denison, Texas, 75020, United States
Southeast Clinical Research Center
TERMINATED

Dalton, Georgia, 30720, United States
Southern California Research Center
TERMINATED

Coronado, California, 92218, United States
St. Josefs-Hospital Wiesbaden
RECRUITING

Wiesbaden, 65189, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Tampa General Hospital
RECRUITING

Tampa, Florida, 33606, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Teine Keijinkai Hospital
RECRUITING

Hokkaido, 006-8555, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310003, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130031, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Liver Institute at Methodist Dallas Medical Center
RECRUITING

Dallas, Texas, 75203, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Tel Aviv Sourasky Medical Center
TERMINATED

Tel Aviv, 6423906, Israel
Toranomon Hospital
RECRUITING

Tokyo, 105-8470, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
UC Davis
RECRUITING

Sacramento, California, 95817, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
UF Health Gastroenterology- Emerson
TERMINATED

Jacksonville, Florida, 32209, United States
UF Hepatology Research at CTRB
RECRUITING

Gainesville, Florida, 32610, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
UZ Gent
RECRUITING

Ghent, 9000, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universita Politecnica delle Marche- Ospedali Riuniti
RECRUITING

Ancona, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitair Ziekenhuis Antwerpe UZA
RECRUITING

Antwerp, 2650, Belgium

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Munster
RECRUITING

Münster, 48149, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Southampton NHS Foundation Trust
RECRUITING

Southampton, Hampshire, S016 6YD, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Tübingen Medical clinic
RECRUITING

Tübingen, 72076, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Zurich(USZ)
RECRUITING

Zurich, 8091, Switzerland

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital, LHSC
RECRUITING

London, Ontario, N6A5A5, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospitals Birmingham NHS Foundation Trust of Trust Headquarters
RECRUITING

Birmingham, West Midlands, B15 2GW, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Alberta
RECRUITING

Edmonton, T6G 2X8, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Iowa Hospitals & Clinics
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
University of Utah Health Care
RECRUITING

Salt Lake City, Utah, 84132, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Frankfurt am Main
RECRUITING

Frankfurt, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Leipzig, Klinik und Poliklinik für Onkologie, Gastroenterologie, Hepatologie und Pneumologie
RECRUITING

Leipzig, 04103, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
Universitätsklinikum Schleswig-Holstein
RECRUITING

Kiel, 24105, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••
Virtua Center for Liver Disease-Camden
RECRUITING

Camden, New Jersey, 08103, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Yale University Digestive Diseases
RECRUITING

New Haven, Connecticut, 06510, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

PBC PRIMARY BILIARY CHOLANGITIS