Kidney drug trial pulled before it even started

NCT ID NCT06598631

Terminated Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study was designed to test whether volenrelaxin could help adults with chronic kidney disease by reducing protein in the urine and preserving kidney function. It was a phase 2, placebo-controlled trial planned to last about 24 weeks. However, the study was withdrawn before enrolling any participants, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: volenrelaxin (also known as LY3540378)

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE

Contacts and locations

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Locations

Beijing Anzhen Hospital, Capital Medical University

Beijing, Beijing Municipality, 100029, China
CHUAC-Complejo Hospitalario Universitario A Coruña

A Coruña, A Coruña [La Coruña], 15006, Spain
Diabetes and Metabolism Associates, APMC

Metairie, Louisiana, 70006, United States
Eastern Nephrology Associates

Jacksonville, North Carolina, 28546, United States
Eastern Nephrology Associates - Greenville

Greenville, North Carolina, 27834, United States
Eastern Nephrology Associates - Wilmington

Wilmington, North Carolina, 28401, United States
Eastern Nephrology Associates- Kinston Office

Kinston, North Carolina, 28504, United States
Eastern Nephrology Associates- New Bern Office

New Bern, North Carolina, 28562, United States
Elite Clinical Research Center

Flint, Michigan, 48532, United States
Endocrine Associates

Houston, Texas, 77004, United States
Fiona Stanley Hospital

Murdoch, Western Australia, 6150, Australia
Hospital Clinico de Valencia

Valencia, Valenciana, Comunitat, 46010, Spain
Hospital Ribera Polusa

Lugo, Lugo [Lugo], 27004, Spain
Hospital Universitari Vall d'Hebron

Barcelona, Barcelona [Barcelona], 08035, Spain
Hospital Universitario Puerta de Hierro Majadahonda

Majadahonda, Madrid, Comunidad de, 28222, Spain
Hospital Universitario Virgen de la Victoria

Málaga, Andalusia, 29010, Spain
Liverpool Hospital

Liverpool, New South Wales, 2170, Australia
Lucas Research, Inc.

Morehead City, North Carolina, 28557, United States
Nephrology Associates of Northern Illinois and Indiana (NANI) - Fort Wayne

Fort Wayne, Indiana, 46804, United States
Nephrology Associates of Northern Illinois and Indiana (NANI) - Hinsdale

Hinsdale, Illinois, 60521, United States
Nephrology Associates of Northern Illinois and Indiana (NANI) - Huntley

Huntley, Illinois, 60142, United States
Nephrology Associates of Northern Illinois and Indiana - IKS - Indianapolis South

Indianapolis, Indiana, 46227, United States
Niigata University Medical & Dental Hospital

Niigata, 951-8520, Japan
Ningbo 2nd Hospital

Ningbo, Zhejiang, 315000, China
Okayama University Hospital

Okayama, 700-8558, Japan
Peking University First Hospital

Beijing, Beijing Municipality, 100034, China
Permian Research Foundation

Odessa, Texas, 79761, United States
Rancho Research Institute

Downey, California, 90242, United States
Renal Research - Gosford

Gosford, New South Wales, 2250, Australia
Southwest Nephrology Associates

Evergreen Park, Illinois, 60805, United States
Taian City Central Hospital

Taian, Shandong, 271000, China
Takai Internal Medicine Clinic

Kamakura-shi, Kanagawa, 247-0056, Japan
The Royal Melbourne Hospital

Parkville, Victoria, 3050, Australia
The first affiliated hospital of Ningbo university

Ningbo, Zhejiang, 315010, China
Yantai Yuhuangding Hospital

Yantai, Shandong, 264099, China

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