Gene therapy injection shows promise for leg pain and ulcers

NCT ID NCT00696124

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested the safety of a gene therapy called VM202 in 12 people with critical limb ischemia, a severe form of leg artery disease causing pain and ulcers. Participants received injections into their leg muscles and were monitored for side effects and pain relief over a year. The goal was to see if the treatment is safe enough for further testing.

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Conditions

The condition(s) this trial relates to.

Chronic Limb-Threatening Ischemia limb ischemia peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Minneapolis Heart Institute Foundation/ Abbott Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States