New drug combo aims to tame rare artery disease

NCT ID NCT07451665

First seen Mar 11, 2026 · Last updated Jun 08, 2026 · Updated 12 times

Summary

This study tests two new drugs, vunakizumab and ivarmacitinib, for people with active Takayasu arteritis (TAK), a rare disease that causes inflammation in large blood vessels. The trial will enroll 180 adults aged 18-70 whose disease is still active despite standard treatments. Researchers will compare the drugs' ability to control the disease over 52 weeks, aiming to reduce reliance on steroids.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital Capital Medical University

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Jiangsu Province Hospital

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Jiaozuo People's Hospital

    Jiaozuo, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, China

  • People's Hospital of Guangxi Zhuang Autonomous Region

    Nanning, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • People's Hospital of Ningxia Hui Autonomous Region

    Yinchuan, Ningxia, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • People's Hospital of Xinjiang Uygur Autonomous Region

    Ürümqi, Xinjiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Shenzhen People's Hospital

    Shenzhen, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The Affiliated Hospital of Inner Mongolia Medical University

    Hohhot, Neimenggu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Affiliated Hospital of Baotou Medical College

    Baotou, Neimenggu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Affiliated Hospital of Henan University of Science and Technology

    Luoyang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Affiliated Hospital of Sun Yat-sen University

    Guanzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Hospital of China Medical University

    Shenyang, Liaoning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Hospital of Jilin University

    Ch’ang-ch’un, Jilin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The First Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Union Hospital Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Xuanwu Hospital Capital Medical University

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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