Could a cheap vitamin pill boost brain healing after head injury?

NCT ID NCT07269457

Recruiting now Disease control Sponsor: Lagos State University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether vitamin D3 supplements can reduce inflammation and improve recovery in adults with mild-to-moderate traumatic brain injury. Researchers will give different doses of vitamin D3 or a placebo to 240 participants and track their blood markers and neurological function for 24 weeks. The goal is to see if this safe, low-cost supplement can become a standard treatment for brain injury recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol)
What this could lead to: If it works, this could point toward a simple, low-cost way to help the brain heal after a head injury, especially in places with limited resources.
What could go wrong: This is an early phase 2 trial with only 240 people, so results may not apply to everyone. Vitamin D is generally safe, but high doses can cause side effects like kidney stones.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic Neuroinflammatory Diseases neuronitis traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROINFLAMMATION TRAUMATIC BRAIN INJURY (TBI) PATIENTS

Contacts and locations

Locations

Lagos State University Teaching Hospital
RECRUITING

Lagos, Nigeria

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