Heart health: do everyday supplements lower blood pressure?

NCT ID NCT01653678

Ongoing Disease control Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking daily vitamin D and omega-3 (fish oil) supplements can help prevent high blood pressure or lower it in healthy adults. Over 25,000 people are taking part, with a smaller group having their blood pressure monitored around the clock. The goal is to see if these common supplements make a real difference for heart health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D3 (cholecalciferol) and omega-3 fatty acids (fish oil)
What this could lead to: If it works, this could show that simple, affordable supplements help manage blood pressure and reduce the risk of hypertension.
What could go wrong: This is an observational analysis within a larger trial, not a dedicated treatment study. Results may be modest or not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

Brigham and Women's Hospital

Boston, Massachusetts, 02215, United States

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Other studies related to the condition(s) this trial covers.