Massive study finds vitamin d and fish oil fail to prevent depression

NCT ID NCT01696435

First seen Dec 15, 2025 · Last updated May 07, 2026 · Updated 22 times

Summary

This study looked at whether taking daily vitamin D or fish oil supplements could prevent depression in over 18,000 healthy adults. Participants had no major depression history and took supplements or placebos for about 5 years. The results showed that neither vitamin D nor fish oil reduced the risk of developing depression or improved mood scores compared to placebo.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.