Virtual reality goggles could make ketamine therapy more comfortable

NCT ID NCT06139016

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study explores whether virtual reality goggles and noise-cancelling headphones can make ketamine/esketamine treatment for depression more tolerable and effective. Participants receive a single treatment while immersed in a relaxing virtual environment. The goal is to see if controlling what patients see and hear during the infusion improves their experience and outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketamine/esketamine

What this could lead to

If it works, this could point toward a way to make ketamine/esketamine treatment more comfortable and effective for people with depression.

What could go wrong

This is a very small, early study with only 7 participants, so results may not apply widely. The virtual reality setup might not improve tolerability or effectiveness as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yale Psychiatry Hospital Interventional Psychiatry Services (IPS) unit

    New Haven, Connecticut, 06520, United States