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Virtual worlds could help men with HIV fight heart disease

NCT ID NCT05242952

Disease control Sponsor: Yale University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether a virtual environment (VE) can help minority men who have sex with men and are living with HIV adopt healthier behaviors to prevent cardiovascular disease. Participants use a computer-based virtual world to access educational quests and other features. The study measures how feasible and acceptable this approach is, and whether it leads to changes in health indicators like body mass index.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a virtual environment (VE) gaming intervention
What this could lead to
If successful, this approach could offer a new, engaging way to help people with HIV reduce their risk of heart disease and other related health problems.
What could go wrong
This is a small, early-stage study focused on feasibility and acceptability, so it may not show clear health benefits. The virtual environment may not be effective or engaging for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

78 people

The number who actually took part.

Started

May 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * identify as an ethnic/racial minority with HIV * identify as gay, same-gender-loving, or MSM * able to read and understand English * access to a computer capable of downloading and running the VE software * no medical history of serious cardiovascular or cognitive complications Exclusion Criteria: Anything outside of inclusion parameters, including history of: * myocardial infarction (MI) * congestive heart failure (CHF) * coronary artery bypass graft (CABG) * cerebral vascular accident (CVA) * cognitive impairment

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Coitus HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases

Contacts and locations

Locations

  • Yale University

    Orange, Connecticut, 06477, United States

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