Brain tumor drug implant under the microscope: how safe is it?
NCT ID NCT02684838
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study followed 272 people with brain tumors who received Gliadel Wafer, a chemotherapy implant placed during surgery. Researchers tracked how long patients lived and whether the tumor came back, as well as any side effects. The goal was to see how the treatment works in real-world medical practice, not in a strict research setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Gliadel Wafer (carmustine implant)
What this could lead to
If successful, this registry will provide real-world data on how well Gliadel Wafer works and its safety in everyday medical practice for brain tumors.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It does not test a new treatment, only monitors existing use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Albany Medical Center Hospital
Albany, New York, 12208, United States
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Baptist Health Paducah
Paducah, Kentucky, 42003, United States
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Baycare Medical Group
Tampa, Florida, 33607, United States
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Beacon Medical Group
Elkhart, Indiana, 46530, United States
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Borrow Neurological Institute
Phoenix, Arizona, 85013, United States
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Brain Tumor Center
Lake Success, New York, 11042, United States
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Crouse Neuroscience Institute
Syracuse, New York, 13210, United States
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Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, 03756, United States
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David Geffen School of Medicine at UCLA; Departments of Neurosurgery and Pathology at the
Los Angeles, California, 90095, United States
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Depaul Hospital
Bridgeton, Missouri, 63044, United States
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Emory University Hospital
Atlanta, Georgia, 30322, United States
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Grand Strand Medical Center
Myrtle Beach, South Carolina, 39572, United States
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Henry Ford Health System
Detroit, Michigan, 48202, United States
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Jfk Medical Center
Edison, New Jersey, 08820, United States
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Johns Hopkins University School of Medicine
Baltimore, Maryland, 21287, United States
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McLaren Bay Neurology Associates
Bay City, Michigan, 48707, United States
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Mount Carmel Neurosurgery
Columbus, Ohio, 43222, United States
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Neurological Associates of Tucson, DBA Center for Neurosciences
Tucson, Arizona, 85718, United States
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Oschner Medical Center
New Orleans, Louisiana, 70121, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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Spine Group Arizona At Honorhealth Scottsdale Osborn Medical Center
Scottdale, Arizona, 85251, United States
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Spine and Neuro Center
Huntsville, Alabama, 35801, United States
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St. Louis University Hospital
St Louis, Missouri, 63110, United States
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University of California, San Francisco Department of Neurological Surgery
San Francisco, California, 94143, United States
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University of Colorado School of Medicine
Aurora, Colorado, 80045, United States
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University of Oklahoma - Stevenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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University of Pennsylvania Health System
Philadelphia, Pennsylvania, 19104, United States
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University of Washington School of Medicine
Seattle, Washington, 98195, United States
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Vidant Medical Center
Greenville, North Carolina, 27834, United States
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Wake Forest Baptist Med Center
Winston-Salem, North Carolina, 27157, United States
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Western Regional Ctr for Brain and Spine Surgery
Las Vegas, Nevada, 89102, United States