Brain tumor drug implant under the microscope: how safe is it?

NCT ID NCT02684838

Completed Knowledge-focused Sponsor: Arbor Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 272 people with brain tumors who received Gliadel Wafer, a chemotherapy implant placed during surgery. Researchers tracked how long patients lived and whether the tumor came back, as well as any side effects. The goal was to see how the treatment works in real-world medical practice, not in a strict research setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Gliadel Wafer (carmustine implant)
What this could lead to: If successful, this registry will provide real-world data on how well Gliadel Wafer works and its safety in everyday medical practice for brain tumors.
What could go wrong: This is an observational study, not a controlled trial, so results may be influenced by other factors. It does not test a new treatment, only monitors existing use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

central nervous system cancer central nervous system neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CNS TUMOR

Contacts and locations

Locations

Albany Medical Center Hospital

Albany, New York, 12208, United States
Baptist Health Paducah

Paducah, Kentucky, 42003, United States
Baycare Medical Group

Tampa, Florida, 33607, United States
Beacon Medical Group

Elkhart, Indiana, 46530, United States
Borrow Neurological Institute

Phoenix, Arizona, 85013, United States
Brain Tumor Center

Lake Success, New York, 11042, United States
Crouse Neuroscience Institute

Syracuse, New York, 13210, United States
Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States
David Geffen School of Medicine at UCLA; Departments of Neurosurgery and Pathology at the

Los Angeles, California, 90095, United States
Depaul Hospital

Bridgeton, Missouri, 63044, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Grand Strand Medical Center

Myrtle Beach, South Carolina, 39572, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Jfk Medical Center

Edison, New Jersey, 08820, United States
Johns Hopkins University School of Medicine

Baltimore, Maryland, 21287, United States
McLaren Bay Neurology Associates

Bay City, Michigan, 48707, United States
Mount Carmel Neurosurgery

Columbus, Ohio, 43222, United States
Neurological Associates of Tucson, DBA Center for Neurosciences

Tucson, Arizona, 85718, United States
Oschner Medical Center

New Orleans, Louisiana, 70121, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Spine Group Arizona At Honorhealth Scottsdale Osborn Medical Center

Scottdale, Arizona, 85251, United States
Spine and Neuro Center

Huntsville, Alabama, 35801, United States
St. Louis University Hospital

St Louis, Missouri, 63110, United States
University of California, San Francisco Department of Neurological Surgery

San Francisco, California, 94143, United States
University of Colorado School of Medicine

Aurora, Colorado, 80045, United States
University of Oklahoma - Stevenson Cancer Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania Health System

Philadelphia, Pennsylvania, 19104, United States
University of Washington School of Medicine

Seattle, Washington, 98195, United States
Vidant Medical Center

Greenville, North Carolina, 27834, United States
Wake Forest Baptist Med Center

Winston-Salem, North Carolina, 27157, United States
Western Regional Ctr for Brain and Spine Surgery

Las Vegas, Nevada, 89102, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.