Withdrawn study: could adding a pill to botox tame overactive bladder?

NCT ID NCT06438861

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study planned to see if adding the daily pill vibegron to standard Botox bladder injections helps women with overactive bladder that hasn't improved with other treatments. Researchers aimed to compare changes in urgent leaks and symptom distress over 12 weeks. However, the trial was withdrawn before any participants were enrolled, so no new information was gathered.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Vibegron (a daily pill) plus onabotulinumtoxinA (Botox) injections into the bladder
What this could lead to
If it had worked, this could point toward a more effective combination treatment for women with stubborn overactive bladder symptoms.
What could go wrong
The trial was withdrawn before enrolling anyone, so no results are available. Combination therapy for overactive bladder is still experimental and may not prove better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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