New hope for lupus kidney patients as experimental drug enters trial
NCT ID NCT05201469
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 20 times
Summary
This study tests whether adding the experimental drug VIB4920 to standard lupus kidney treatments (mycophenolate mofetil and prednisone) can improve kidney function in people with active lupus nephritis. About 74 adults with lupus and kidney inflammation will receive either VIB4920 or a placebo, and researchers will measure how many achieve normal protein levels in urine and stable kidney function by 36 weeks. The goal is to find a more effective way to control this serious complication of lupus.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Columbia University Medical Center: Department of Medicine, Division of Rheumatology
RECRUITINGNew York, New York, 10032, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Emory University School of Medicine: Division of Rheumatology
RECRUITINGAtlanta, Georgia, 30307, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Feinstein Institute for Medical Research: Center for Autoimmune and Musculoskeletal Diseases
RECRUITINGManhasset, New York, 11030, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital for Special Surgery, New York: Division of Rheumatology
NOT_YET_RECRUITINGNew York, New York, 10021, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Penn State Health Milton S. Hershey Medical Center: Division of Rheumatology
RECRUITINGHershey, Pennsylvania, 17033, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple University, Lewis Katz School of Medicine, Department of Medicine: Nephrology
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UCLA Medical Center: Division of Rheumatology
RECRUITINGLos Angeles, California, 90095, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Diego School of Medicine: Division of Rheumatology, Allergy and Immunology
RECRUITINGLa Jolla, California, 92093, United States
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Chicago, Department of Medicine: Rheumatology
RECRUITINGChicago, Illinois, 60637, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Colorado School of Medicine: Division of Rheumatology
RECRUITINGAurora, Colorado, 80045, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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University of Miami Miller School of Medicine: Nephrology & Hypertension Division
RECRUITINGMiami, Florida, 33136, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Contact Email: •••••@•••••
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University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University School of Medicine in St. Louis: Division of Nephrology
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale University School of Medicine: Section of Rheumatology
RECRUITINGNew Haven, Connecticut, 06519, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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of California, Irvine School of Medicine Division of Rheumatology
RECRUITINGOrange, California, 92868, United States
Contact Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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