New infusion drug hopes to slow Alzheimer's in early stages

NCT ID NCT07094516

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called VHB937 in people with early Alzheimer's disease. About 400 participants will receive either the drug or a placebo by infusion over 72 weeks. The goal is to see if the drug can slow down memory and thinking problems. Researchers will also check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VHB937 (a biologic drug given by infusion)

What this could lead to

If it works, this could point toward a treatment that slows cognitive decline in early Alzheimer's disease.

What could go wrong

This is a Phase 2 trial, so it is still early. The drug may not show benefit or could have side effects. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER S DISEASE

Contacts and locations

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Study contacts

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Abington Neurological Associates Ltd
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Willow Grove, Pennsylvania, 19090, United States

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ActivMed Practices and Research
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Methuen, Massachusetts, 01844, United States

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Alzheimers Research Treatment Ctr
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Wellington, Florida, 33414, United States
Alzheimers Research Treatment Ctr
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Wellington, Florida, 33414, United States

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Banner Alzheimers Institute
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Phoenix, Arizona, 85006, United States

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Charter Research The Villages
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The Villages, Florida, 32162, United States

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Citizens Memorial Hospital Neurology CLinic
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Bolivar, Missouri, 65613, United States

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Conquest Research
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Winter Park, Florida, 32789, United States

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Hawaii Pacific Neuroscience LLC
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Honolulu, Hawaii, 96817, United States

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Irvine Center for Clinical Research
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Irvine, California, 92618, United States

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Jem Research Institute
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Atlantis, Florida, 33462-6608, United States

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K2 Medical Research LLC
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Maitland, Florida, 32751, United States
K2 Medical Research LLC
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Maitland, Florida, 32751, United States

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Lou Ruvo Center for Brain Health
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Las Vegas, Nevada, 89106, United States

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Neural Net Research
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Portland, Oregon, 97225, United States

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Novartis Investigative Site
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Camperdown, New South Wales, 2050, Australia
Novartis Investigative Site
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Kogarah, New South Wales, 2217, Australia
Novartis Investigative Site
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Box Hill, Victoria, 3128, Australia
Novartis Investigative Site
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Heidelberg, Victoria, 3084, Australia
Novartis Investigative Site
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Nedlands, Western Australia, 6009, Australia
Novartis Investigative Site
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London, Ontario, N6G 3H7, Canada
Novartis Investigative Site
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North York, Ontario, M6A 2C8, Canada
Novartis Investigative Site
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Ottawa, Ontario, K1N 5C8, Canada
Novartis Investigative Site
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Toronto, Ontario, M3B 2S7, Canada
Novartis Investigative Site
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Toronto, Ontario, M5T 2S8, Canada
Novartis Investigative Site
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Hangzhou, Zhejiang, 310002, China
Novartis Investigative Site
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Shanghai, 200040, China
Novartis Investigative Site
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Brno, 602 00, Czechia
Novartis Investigative Site
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Prague, 160 00, Czechia
Novartis Investigative Site
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Toulouse, Haute Garonne, 31059, France
Novartis Investigative Site
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Paris, 75013, France
Novartis Investigative Site
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Berlin, State of Berlin, 12200, Germany
Novartis Investigative Site
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Berlin, 13353, Germany
Novartis Investigative Site
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München, 80377, Germany
Novartis Investigative Site
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Cefalù, PA, 90015, Italy
Novartis Investigative Site
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Perugia, PG, 06129, Italy
Novartis Investigative Site
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Ōbu, Aichi-ken, 4748511, Japan
Novartis Investigative Site
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Fujioka, Gunma, 375-0017, Japan
Novartis Investigative Site
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Itabashi Ku, Tokyo, 1730015, Japan
Novartis Investigative Site
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Kodaira, Tokyo, 187-8551, Japan
Novartis Investigative Site
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Shinjuku Ku, Tokyo, 160-0023, Japan
Novartis Investigative Site
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Amsterdam, 1081 GN, Netherlands
Novartis Investigative Site
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Bialystok, 15-756, Poland
Novartis Investigative Site
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Oświęcim, 32-600, Poland
Novartis Investigative Site
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Wroclaw, 53659, Poland
Novartis Investigative Site
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Seoul, Korea, 05505, South Korea
Novartis Investigative Site
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Seoul, Seoul, 03080, South Korea
Novartis Investigative Site
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Seoul, Seoul, 05030, South Korea
Novartis Investigative Site
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Incheon, 21565, South Korea
Novartis Investigative Site
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Incheon, 22332, South Korea
Novartis Investigative Site
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Seoul, 04763, South Korea
Novartis Investigative Site
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Pamplona, Navarre, 31008, Spain
Novartis Investigative Site
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Valencia, Valencia, 46017, Spain
Novartis Investigative Site
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Valencia, 46026, Spain
Novartis Investigative Site
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Mölndal, 431 80, Sweden
Novartis Investigative Site
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Stockholm, 141 86, Sweden
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Edinburgh, Lothian, EH12 5PJ, United Kingdom
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Oxford, Oxfordshire, OX3 7JX, United Kingdom
Novartis Investigative Site
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Aberdeen, AB25 2ZH, United Kingdom
Novartis Investigative Site
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London, SE5 8AF, United Kingdom
Novartis Investigative Site
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London, W1G 9JF, United Kingdom
Novartis Investigative Site
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London, WC1N 3BG, United Kingdom
Novartis Investigative Site
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Newcastle upon Tyne, NE4 6BE, United Kingdom
Novartis Investigative Site
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Salford, M6 8HD, United Kingdom
Novartis Investigative Site
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Southampton, SO16 6YD, United Kingdom
Renstar Medical Research
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Ocala, Florida, 34471, United States

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The Ohio State University
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Columbus, Ohio, 43210, United States

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UNC Hosp Invest Drug Serv Pharm
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Chapel Hill, North Carolina, 27514, United States

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University of California San Diego
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La Jolla, California, 92037, United States

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University of California at Los Angeles
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Los Angeles, California, 90095, United States

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University of Kansas Hospital
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Fairway, Kansas, 66205, United States

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University of Texas Health Science Center at San Antonio
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San Antonio, Texas, 78229-3900, United States

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University of Washington Medical Center
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Seattle, Washington, 98195, United States

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Visionary Investigators Network
RECRUITING

Aventura, Florida, 33180, United States

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