New infusion drug hopes to slow Alzheimer's in early stages

NCT ID NCT07094516

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called VHB937 in people with early Alzheimer's disease. About 400 participants will receive either the drug or a placebo by infusion over 72 weeks. The goal is to see if the drug can slow down memory and thinking problems. Researchers will also check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VHB937 (a biologic drug given by infusion)
What this could lead to: If it works, this could point toward a treatment that slows cognitive decline in early Alzheimer's disease.
What could go wrong: This is a Phase 2 trial, so it is still early. The drug may not show benefit or could have side effects. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE

Contacts and locations

Locations

Abington Neurological Associates Ltd
RECRUITING

Willow Grove, Pennsylvania, 19090, United States
ActivMed Practices and Research
RECRUITING

Methuen, Massachusetts, 01844, United States
Alzheimers Research Treatment Ctr
RECRUITING

Wellington, Florida, 33414, United States
Alzheimers Research Treatment Ctr
RECRUITING

Wellington, Florida, 33414, United States
Banner Alzheimers Institute
RECRUITING

Phoenix, Arizona, 85006, United States
Charter Research The Villages
RECRUITING

The Villages, Florida, 32162, United States
Citizens Memorial Hospital Neurology CLinic
RECRUITING

Bolivar, Missouri, 65613, United States
Conquest Research
RECRUITING

Winter Park, Florida, 32789, United States
Hawaii Pacific Neuroscience LLC
RECRUITING

Honolulu, Hawaii, 96817, United States
Irvine Center for Clinical Research
RECRUITING

Irvine, California, 92618, United States
Jem Research Institute
RECRUITING

Atlantis, Florida, 33462-6608, United States
K2 Medical Research LLC
RECRUITING

Maitland, Florida, 32751, United States
K2 Medical Research LLC
RECRUITING

Maitland, Florida, 32751, United States
Lou Ruvo Center for Brain Health
RECRUITING

Las Vegas, Nevada, 89106, United States
Neural Net Research
RECRUITING

Portland, Oregon, 97225, United States
Novartis Investigative Site
RECRUITING

Camperdown, New South Wales, 2050, Australia
Novartis Investigative Site
RECRUITING

Kogarah, New South Wales, 2217, Australia
Novartis Investigative Site
RECRUITING

Box Hill, Victoria, 3128, Australia
Novartis Investigative Site
RECRUITING

Heidelberg, Victoria, 3084, Australia
Novartis Investigative Site
RECRUITING

Nedlands, Western Australia, 6009, Australia
Novartis Investigative Site
RECRUITING

London, Ontario, N6G 3H7, Canada
Novartis Investigative Site
RECRUITING

North York, Ontario, M6A 2C8, Canada
Novartis Investigative Site
RECRUITING

Ottawa, Ontario, K1N 5C8, Canada
Novartis Investigative Site
RECRUITING

Toronto, Ontario, M3B 2S7, Canada
Novartis Investigative Site
RECRUITING

Toronto, Ontario, M5T 2S8, Canada
Novartis Investigative Site
RECRUITING

Hangzhou, Zhejiang, 310002, China
Novartis Investigative Site
RECRUITING

Shanghai, 200040, China
Novartis Investigative Site
RECRUITING

Brno, 602 00, Czechia
Novartis Investigative Site
RECRUITING

Prague, 160 00, Czechia
Novartis Investigative Site
RECRUITING

Toulouse, Haute Garonne, 31059, France
Novartis Investigative Site
RECRUITING

Paris, 75013, France
Novartis Investigative Site
RECRUITING

Berlin, State of Berlin, 12200, Germany
Novartis Investigative Site
RECRUITING

Berlin, 13353, Germany
Novartis Investigative Site
RECRUITING

München, 80377, Germany
Novartis Investigative Site
RECRUITING

Cefalù, PA, 90015, Italy
Novartis Investigative Site
RECRUITING

Perugia, PG, 06129, Italy
Novartis Investigative Site
RECRUITING

Ōbu, Aichi-ken, 4748511, Japan
Novartis Investigative Site
RECRUITING

Fujioka, Gunma, 375-0017, Japan
Novartis Investigative Site
RECRUITING

Itabashi Ku, Tokyo, 1730015, Japan
Novartis Investigative Site
RECRUITING

Kodaira, Tokyo, 187-8551, Japan
Novartis Investigative Site
RECRUITING

Shinjuku Ku, Tokyo, 160-0023, Japan
Novartis Investigative Site
RECRUITING

Amsterdam, 1081 GN, Netherlands
Novartis Investigative Site
RECRUITING

Bialystok, 15-756, Poland
Novartis Investigative Site
RECRUITING

Oświęcim, 32-600, Poland
Novartis Investigative Site
RECRUITING

Wroclaw, 53659, Poland
Novartis Investigative Site
RECRUITING

Seoul, Korea, 05505, South Korea
Novartis Investigative Site
RECRUITING

Seoul, Seoul, 03080, South Korea
Novartis Investigative Site
RECRUITING

Seoul, Seoul, 05030, South Korea
Novartis Investigative Site
RECRUITING

Incheon, 21565, South Korea
Novartis Investigative Site
RECRUITING

Incheon, 22332, South Korea
Novartis Investigative Site
RECRUITING

Seoul, 04763, South Korea
Novartis Investigative Site
RECRUITING

Pamplona, Navarre, 31008, Spain
Novartis Investigative Site
RECRUITING

Valencia, Valencia, 46017, Spain
Novartis Investigative Site
RECRUITING

Valencia, 46026, Spain
Novartis Investigative Site
RECRUITING

Mölndal, 431 80, Sweden
Novartis Investigative Site
RECRUITING

Stockholm, 141 86, Sweden
Novartis Investigative Site
RECRUITING

Edinburgh, Lothian, EH12 5PJ, United Kingdom
Novartis Investigative Site
RECRUITING

Oxford, Oxfordshire, OX3 7JX, United Kingdom
Novartis Investigative Site
RECRUITING

Aberdeen, AB25 2ZH, United Kingdom
Novartis Investigative Site
RECRUITING

London, SE5 8AF, United Kingdom
Novartis Investigative Site
RECRUITING

London, W1G 9JF, United Kingdom
Novartis Investigative Site
RECRUITING

London, WC1N 3BG, United Kingdom
Novartis Investigative Site
RECRUITING

Newcastle upon Tyne, NE4 6BE, United Kingdom
Novartis Investigative Site
RECRUITING

Salford, M6 8HD, United Kingdom
Novartis Investigative Site
RECRUITING

Southampton, SO16 6YD, United Kingdom
Renstar Medical Research
RECRUITING

Ocala, Florida, 34471, United States
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
UNC Hosp Invest Drug Serv Pharm
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of California San Diego
RECRUITING

La Jolla, California, 92037, United States
University of California at Los Angeles
RECRUITING

Los Angeles, California, 90095, United States
University of Kansas Hospital
RECRUITING

Fairway, Kansas, 66205, United States
University of Texas Health Science Center at San Antonio
RECRUITING

San Antonio, Texas, 78229-3900, United States
University of Washington Medical Center
RECRUITING

Seattle, Washington, 98195, United States
Visionary Investigators Network
RECRUITING

Aventura, Florida, 33180, United States

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