Could a common mood stabilizer and cholesterol drug boost chemo for pancreatic cancer?

NCT ID NCT05821556

First seen May 12, 2026 · Last updated May 12, 2026

Summary

This study tests whether adding valproic acid and simvastatin to standard chemotherapy can help people with advanced pancreatic cancer that has spread. About 240 adults who have not had prior treatment will be randomly assigned to receive either the standard chemo or the standard chemo plus the two extra drugs. The main goal is to see if the new combination delays cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Istituto Nazionale Tumori di Napoli - IRCCS - Fondazione G. Pascale

    RECRUITING

    Naples, Italy, 80131, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ramon y Cajal Hospital and Health Research Institute (IRYCIS)

    RECRUITING

    Madrid, Madrid, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Verona Hospital Trust

    RECRUITING

    Verona, Verona, 37122, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Università Cattolica Del Sacro Cuore, IRCCS Fondazione Policlinico Universitario Gemelli - Medical Oncology, Roma, Italia

    RECRUITING

    Roma, Roma, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Università vita e Salute, IRCCS San Raffaele

    RECRUITING

    Milan, Milano, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.