New balloon procedure could prevent stroke in High-Risk patients

NCT ID NCT03729817

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called submaximal balloon angioplasty to improve blood flow in narrowed brain arteries and prevent stroke. It involves 159 people who recently had a mild stroke due to severe artery narrowing (70-99%). The procedure uses a small balloon inflated to a smaller size than the normal artery to widen the vessel. The goal is to see if it is safe and works well enough to plan a larger trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

submaximal balloon angioplasty

What this could lead to

If successful, this procedure could offer a new treatment option to prevent stroke in patients with intracranial artery narrowing who have no other options.

What could go wrong

This is an early-stage safety and feasibility study with only 159 participants. The procedure carries risks of stroke or death, and it may not prove effective or durable.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intracranial arterial disease intracranial arteriosclerosis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••